Lizzy Caplan (born June 30, 1982) is an American actor, known for her role as Virigina E. Johnson on the series Masters of Sex. She portrayed Annie Wilkes in the second season of the Hulu television series Castle Rock.
She has received wide recognition with roles in the films Mean Girls (2004) and Cloverfield (2008), the latter of which earned her a nomination for the Saturn Award for Best Supporting Actress. Caplan has also starred on the TV shows Related (2005–2006), The Class (2006–2007), and Party Down (2009–2010). From 2013 to 2016, she played Virginia E. Johnson on the Showtime series Masters of Sex, a role for which she received nominations for a Primetime Emmy, two Satellite Awards, and a Critics' Choice Award. Her other film appearances include Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Extinction (2018).